Ethical concerns about altering the human germline, which could lead to irreversible and heritable consequences for future generations, are the primary driver of controversy surrounding gene editing.

CURRENT STATE

These ethical concerns fuel global debate and regulatory caution, evidenced by near-universal bans on embryo editing and calls for frameworks that distinguish therapeutic use from enhancement. This underpins public apprehension, despite advances in technologies like CRISPR and emerging regulatory pathways like the FDA's February 2026 draft guidance.

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